Here is how I am currently configuring my InTank basket in chamber one. If anyone has a suggestion on how to improve let me know. I replace the top shelf filter floss twice a week (once mid week, and once again on water change day). The bottom shelf filter floss gets replaced one a week on water change day. In regards to the ChemiPure in the middle shelf I am planning on replacing it every 3 months. So far so good with parameters, Ammonia, Nitirites, and Nitrates are always 0.