If he doesn't have any filtering media in the wet/dry I'm not sure it will matter. He should have established bacterial filtration in his LR. I do suspect that he might have a small cycle until the bacteria in the LR multiply enough to counter the loss of any bacteria in the canister, but he will probably get that no matter when he removes the canister.
Remember, you have just enough bacteria to balance your current bio-load. Adding the wet/dry while leaving the canister running won't necessarily encourage bacteria to colonize. A better idea would probably be to add the wet/dry and slowly remove the media in your canister until you have an empty canister just pumping water, then remove the canister.